Why tumour cells become resistant to chemotherapy

U of A team discovers new mechanism that could lead to better treatments for breast cancer patients

Why tumour cells become resistant to chemotherapyA team of University of Alberta researchers has identified a new mechanism through which tumour cells become resistant to chemotherapy – a discovery that could lead to better treatments for women with breast cancer. Michael Jewer, a post-doctoral researcher in the Faculty of Medicine & Dentistry, said that more than 20 per cent of breast cancer…

New ‘atlas’ of the heart offers new approach to treating heart disease

Cutting-edge techniques the first step toward understanding heart disease and developing new targeted treatments to stop it

New ‘atlas’ of the heart offers new approach to treating heart diseaseScientists have for the first time documented all of the different cell types and genes expressed in the healthy human heart, in research published recently in the journal Nature. Cardiologists from the Mazankowski Alberta Heart Institute at the University of Alberta joined teams from Cambridge, Boston and Berlin to use state-of-the-art analytical techniques to sequence the ribonucleic acids (RNA)…

Antiviral drug remdesivir offers second mechanism of attack

Understanding how the conditionally approved COVID-19 drug works is key to improving treatments, says U of A researcher

Antiviral drug remdesivir offers second mechanism of attackResearchers at the University of Alberta have discovered a novel, second mechanism of action by the antiviral drug remdesivir against SARS-CoV-2, according to findings published in the Journal of Biological Chemistry. The research team previously demonstrated how remdesivir inhibits the COVID-19 virus’s polymerase or replication machinery in a test tube. Matthias Götte, chair of medical microbiology and immunology…

Wildfires, logging affect key fungi in pine forests: studies

Disturbances by humans or nature change the balance of fungi in soil, potentially making it harder for seedlings to regenerate

Wildfires, logging affect key fungi in pine forests: studiesDisturbances can hit Alberta’s lodgepole pine forests hard – including life under the soil, new University of Alberta research shows. Fungal communities that nourish pine tree roots are being altered by both human-made and natural disturbances, which can stress forests and make it tougher for pine seedlings to regenerate, said Jean Rodriguez Ramos, a PhD…

Little evidence vitamin D prevents severe COVID-19

Getting too much vitamin D can also cause health problems, says U of A pediatric kidney specialist

Little evidence vitamin D prevents severe COVID-19At the beginning of May, a pair of studies emerged suggesting people who are deficient in vitamin D are more likely to experience serious health complications if infected with COVID-19. Sales of the micronutrient soared as a scared public tried to gain any advantage they could over the virus. Unfortunately, University of Alberta pediatrics professor Todd…

Group designs better CPR board for resuscitating COVID-19 patients

Pandemic inspires University of Alberta innovation in emergency and critical care

Group designs better CPR board for resuscitating COVID-19 patientsA potential need sparked by the COVID-19 pandemic has inspired an Edmonton team of clinicians and academics to build a better cardiopulmonary resuscitation (CPR) board for use in emergency departments and intensive care units (ICUs). Because of COVID-19’s attack on the lungs, many patients in emergency departments and intensive care are placed on their bellies…

Forensic anthropologist helps police identify unknown victims

For Pamela Mayne Correia, the most satisfying cases are the ones she helps solve with the scarcest of skeletal remains

Forensic anthropologist helps police identify unknown victimsForensic anthropology requires guts of steel but there was one disturbing case even Pamela Mayne Correia found hard to stomach. The University of Alberta anthropologist was called in to help reconstruct and identify human remains after one of Canada’s worst mass murders, the 1992 bombing of nine replacement workers during a strike-lockout at the Giant gold mine in…

Butterflies ‘sentinels’ of climate change in mountain ecosystems

U of A scientists urge more monitoring of butterfly populations to help understand alpine environments predicted to change rapidly

Butterflies ‘sentinels’ of climate change in mountain ecosystemsMountains and butterflies are conceptualized as the ultimate juxtaposition – enduring and resolute versus fleeting and delicate – but the surprising robustness of alpine butterflies could help scientists better understand the impact climate change is having on mountains. In an essay written for the third annual State of the Mountains report by the Alpine Club of Canada, University…

Neonatal heart surgery survivors face kidney, blood pressure issues

Neonatal heart surgery survivors face kidney, blood pressure issuesBabies who have life-saving surgery for congenital heart problems within the first month of life face a lifelong risk of chronic kidney disease and high blood pressure, according to new research led by University of Alberta pediatric specialists. “We know that kidneys, like all organs, have to last a lifetime,” said Catherine Morgan, associate professor and interim…

Is alien life floating in the clouds of Venus?

There’s a good chance the global shift from skepticism to possibility about extraterrestrial life is about to extend even further

Is alien life floating in the clouds of Venus?Is there life on other planets? That question has intrigued man for generations. Most people used to scoff at the suggestion of the existence of UFOs and tales of little green men from Mars (or worse). Societal attitudes have shifted due to our increased fascination with Roswell/UFO sightings, Phoenix Lights, Lubbock Lights, and depictions of…
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